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Infantile bullous pemphigoid successfully treated with combined pulse corticosteroids and high‐dose IVIG
Author(s) -
Wawrzycki Bartlomiej,
Krasowska Dorota,
Pietrzak Aldona,
Szumilo Justyna,
Blazowski Lukasz,
PietraszekMamcarz Jolanta,
Lotti Torello
Publication year - 2018
Publication title -
dermatologic therapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.595
H-Index - 68
eISSN - 1529-8019
pISSN - 1396-0296
DOI - 10.1111/dth.12635
Subject(s) - medicine , bullous pemphigoid , dermatology , pemphigoid , methylprednisolone , antibody , immunology , surgery
Bullous pemphigoid is the most common autoimmune blistering disorder in the elderly. It affects people aged 70 years or older. Clinically it is characterized by intensely pruritic eruption consisting of widespread tense blisters on an erythematous background. It is associated with cellular and humoral responses against hemidesmosomal components of the skin and mucous membranes. In contrast, infantile bullous pemphigoid is exceedingly rare disease and presents with some unique features like favorable prognosis, possible association with vaccination, and primary involvement of acral surfaces. Herein, we present a case of 4,5‐month‐old infant with neonatal pemphigoid, successfully treated with a combination of intravenous immunoglobulins and pulse methylprednisolone.