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Adjuvant treatment of chronic plaque psoriasis in adults by a herbal combination: Open German trial and review of the literature
Author(s) -
Wollina Uwe,
França Katlein,
Lotti Torello,
Tirant Michael
Publication year - 2018
Publication title -
dermatologic therapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.595
H-Index - 68
eISSN - 1529-8019
pISSN - 1396-0296
DOI - 10.1111/dth.12624
Subject(s) - medicine , psoriasis , plaque psoriasis , dermatology , adverse effect , adjuvant , randomized controlled trial , quality of life (healthcare) , clinical trial , dermatology life quality index , open label , population , adjuvant therapy , surgery , chemotherapy , nursing , environmental health
Psoriasis is a chronic inflammatory skin disease affecting up to 6% of the World population. Skin care is the basic approach to restore epidermal barrier function, provide symptomatic relief, and ensure remission‐free periods. We performed an open trial using herbal complex Soratinex® (also known as Dr Michaels®) in adult patients with mild‐to‐moderate chronic plaque psoriasis without further improvement to previous treatments in the last 6 weeks. The products Cleansing Gel, Scalp & Body Ointment, and Skin Conditioner were applied twice daily for 8 weeks. All patients achieved a Psoriasis Area and Severity Index (PASI) 50 response, 94.4% achieved a PASI 75, 66.7% achieved PASI 90, and 22.2% achieved a PASI 100. In week 8, 94.4% of patients were satisfied or very satisfied with the treatment that was well tolerated. We performed a literature review on published trials in children and adults suffering from psoriasis. Herbal complex Soratinex® achieved a PASI 50 or more in about 50–90% of patients. It ensures prolonged relapse‐free periods and improves the quality of life. Adverse events are mild and seen in a minority of patients only. In conclusion, herbal complex allows safe and effective self‐treatment of patients with psoriasis and improves patient's autonomy.