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Resolution of inverse psoriasis after treatment with levodopa for Parkinson's disease
Author(s) -
Rojo Suárez Natalia,
Jiménez Gallo David,
Arjona Aguilera Cintia,
Espinosa Rosso Raúl,
Linares Barrios Mario
Publication year - 2016
Publication title -
dermatologic therapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.595
H-Index - 68
eISSN - 1529-8019
pISSN - 1396-0296
DOI - 10.1111/dth.12408
Subject(s) - medicine , intertriginous , psoriasis , levodopa , dermatology , disease , parkinson's disease , pathology
Inverse psoriasis is characterized by the development of erythematous shiny plaques at intertriginous areas of the body. It has a prevalence of 2% worldwide. The usefulness of levodopa in psoriasis was discovered in 1970 but nowadays it is not a standard therapy for this condition. A 74‐year‐old woman was diagnosed with Parkinson's disease subsequent to the development of extensive inverse psoriasis. The skin lesions were resistant to classical topical and systemic medications. Treatment with levodopa was initiated in order to treat her neurological problem and progressive remission of the skin lesions was noted. We highlight the role of dopamine in the pathophysiology of this dermatosis.