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Granulomatous reaction to liquid injectable silicone for gluteal enhancement: review of management options and success of doxycycline
Author(s) -
Paul Suchismita,
Goyal Amrita,
Duncan Lyn M.,
Smith Gideon P.
Publication year - 2015
Publication title -
dermatologic therapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.595
H-Index - 68
eISSN - 1529-8019
pISSN - 1396-0296
DOI - 10.1111/dth.12204
Subject(s) - medicine , silicone , doxycycline , surgery , antibiotics , chemistry , organic chemistry , microbiology and biotechnology , biology
Liquid injectable silicone ( LIS ) for cosmetic purposes has been widely available and commonly used for almost half a century. An increase in buttock augmentation procedures because of patients wanting to emulate the look of some celebrities has recently highlighted cases in the media of unsafe administration of liquid silicone injections. Severe complications including death have been reported. In this article, we report a case in which liquid silicone was injected in the patient's gluteal tissue resulting in granulomatous reactions in the surrounding tissues. The patient responded well to doxycycline, presumably because of both its antimicrobial properties and immunomodulatory effects.