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Treatment of keloids with laser‐assisted topical steroid delivery: a retrospective study of 23 cases
Author(s) -
Cavalié Marine,
Sillard Laura,
Montaudié Henri,
Bahadoran Philippe,
Lacour JeanPhilippe,
Passeron Thierry
Publication year - 2014
Publication title -
dermatologic therapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.595
H-Index - 68
eISSN - 1529-8019
pISSN - 1396-0296
DOI - 10.1111/dth.12187
Subject(s) - medicine , ablative case , dermatology , scars , keloid , surgery , retrospective cohort study , betamethasone , topical steroid , radiation therapy
Topical or intralesional corticosteroids are referred to as gold standard treatments for keloids. Recent studies showed that ablative fractional laser ( AFL ) treatment facilitates delivery of topical drug deeply into the skin by creating vertical channels. The objective of the present study was to assess the ablative erbium laser in fractionated mode, combined with topical high potent corticosteroid cream for treating resistant keloid scars. We conducted a retrospective study in the laser center of the Department of Dermatology ( U niversity Hospital of N ice, F rance), from J anuary 2010 to J une 2012, on patients with keloids who were resistant to a first‐line of treatment. A 2940‐nm ablative fractional erbium laser was used. Topical betamethasone cream was applied twice a day under occlusion with transparent film dressings. A total of 23 patients with 70 keloids were treated from J anuary 2010 to J une 2012. The median percentage of improvement was 50% (range −43 to 84). The mean follow‐up was 8 months (range 3–18), and a recurrence was observed for eight lesions (22%). Although this observation warrants a prospective comparative evaluation, it supports the interest of the laser‐assisted delivery of steroids for treating keloids scars.