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Successful treatment with narrow‐band UVB therapy for a case of generalized H ailey– H ailey disease with a novel splice‐site mutation in ATP 2 C 1 gene
Author(s) -
Mizuno Kana,
Hamada Takahiro,
Hashimoto Takashi,
Okamoto Hiroyuki
Publication year - 2014
Publication title -
dermatologic therapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.595
H-Index - 68
eISSN - 1529-8019
pISSN - 1396-0296
DOI - 10.1111/dth.12125
Subject(s) - medicine , rna splicing , mutation , hailey–hailey disease , dermatology , disease , genetics , pathology , rna , gene , biology
H ailey– H ailey disease ( HHD ) is a rare autosomal dominant disorder characterized by development of recurrent blisters, erosions, and crustations in the intertriginous areas. The treatment of HHD is often challenging, and various methods have been tried. We report here a case of a 45‐year‐old woman with a generalized form of HHD that was dramatically improved and well controlled by narrow‐band ultraviolet B phototherapy.