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Epidermolysis bullosa pruriginosa showing good response to low‐dose thalidomide – a report of two cases
Author(s) -
Ranugha P. S. S.,
Mohanan S.,
Chandrashekar L.,
Basu D.,
Thappa D. M.,
Rajesh N. G.
Publication year - 2013
Publication title -
dermatologic therapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.595
H-Index - 68
eISSN - 1529-8019
pISSN - 1396-0296
DOI - 10.1111/dth.12047
Subject(s) - medicine , epidermolysis bullosa , thalidomide , dermatology , multiple myeloma
Epidermolysis bullosa pruriginosa is a rare distinctive variant of dystrophic epidermolysis bullosa characterized by intense pruritus, lichenified plaques in linear distribution, and anonychia. It is a difficult condition to treat and causes a great deal of distress. The present authors report two cases showing good response to low‐dose thalidomide, with clinical and symptomatic improvement. The exact mechanism of action is not yet clear.