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Metabolic syndrome in vitiligo
Author(s) -
Pietrzak Aldona,
Bartosińska Joanna,
Hercogová Jana,
Lotti Torello M,
Chodorowska Grażyna
Publication year - 2012
Publication title -
dermatologic therapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.595
H-Index - 68
eISSN - 1529-8019
pISSN - 1396-0296
DOI - 10.1111/dth.12012
Subject(s) - vitiligo , medicine , metabolic syndrome , dermatology , disease , inflammation , adipose tissue , metabolic disease , melanocyte , bioinformatics , diabetes mellitus , endocrinology , melanoma , cancer research , biology
Vitiligo is an acquired, depigmenting skin disease with still unclear, multifactorial etiopathogenesis. However, there is growing evidence that vitiligo affects not only the skin but it may also be connected with metabolic abnormalities, including glucose intolerance and lipid abnormalities, all of which confirms the systemic nature of the disease. Recently, it has been shown that melanocytes, especially those found in the adipose tissue, due to their ability to decrease inflammation and oxidative damage, are capable of preventing the metabolic syndrome. The article presents updated knowledge on potential metabolic disturbances in vitiligo.