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Longevity of the novel ConvaTec infusion set with Lantern technology
Author(s) -
Lal Rayhan A.,
Hsu Liana,
Zhang Jian,
Schøndorff Pernelle K.,
Heschel Matthias,
Buckingham Bruce
Publication year - 2021
Publication title -
diabetes, obesity and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.445
H-Index - 128
eISSN - 1463-1326
pISSN - 1462-8902
DOI - 10.1111/dom.14395
Subject(s) - medicine , lantern , diabetes mellitus , insulin , surgery , endocrinology , chemistry , ring (chemistry) , organic chemistry
Current insulin infusion sets are approved for only 2‐3 days. The novel ConvaTec infusion set with Lantern technology is designed to extend infusion set wear time. The goal of this pilot study was to evaluate the duration of wear for this set. This was a pilot safety study in adults with type 1 diabetes using tethered insulin pumps. Participants inserted the set and wore it for 10 days or until failure. Among 24 participants, two were excluded. Forty‐five per cent of the sets lasted 10 days. Median wear time was 9.1 (7.1, 10.0) days. Among 12 premature failures, six (50%) involved adhesive failures, four (33%) hyperglycaemia unresponsive to correction, one (8%) hyperglycaemia with ketones and one (8%) infection. Average CGM glucose per day of infusion set wear showed a statistically significant increase over time, while total daily insulin over the same period did not change. In this pilot study, the duration of wear for the novel infusion set exceeded previously reported commercial sets ( P < .001). This extended wear technology may eventually allow for a combined glucose sensor and infusion set.