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Association between diabetes mellitus and incidence of intracerebral haemorrhage and case fatality rates: A retrospective population‐based cohort study
Author(s) -
Boulanger Marion,
AlShahi Salman Rustam,
Kerssens Jan,
Wild Sarah H.
Publication year - 2017
Publication title -
diabetes, obesity and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.445
H-Index - 128
eISSN - 1463-1326
pISSN - 1462-8902
DOI - 10.1111/dom.12934
Subject(s) - medicine , case fatality rate , diabetes mellitus , incidence (geometry) , type 2 diabetes , population , retrospective cohort study , cohort study , relative risk , type 1 diabetes , pediatrics , confidence interval , cohort , epidemiology , endocrinology , environmental health , physics , optics
We investigated the associations between diabetes (type 1, type 2 or no diabetes) and intracerebral haemorrhage ( ICH ) incidence as well as case fatality after ICH , in a retrospective cohort study of people aged 40 to 89 years in S cotland during the period 2004 to 2013, using linkage of population‐based records of diagnosed diabetes, hospital discharges and deaths. We calculated ICH incidence and 30‐day case fatality after hospital admission for ICH , along with their relative risks ( RR ) and 95% confidence intervals ( CIs ), among people with type 1 or type 2 diabetes compared to people without diabetes, adjusting for age, sex and socio‐economic status ( SES ). There were 77, 1275 and 9778 incident ICH events and the case‐fatality rate was 44% (95% CI 33, 57), 38% (95% CI 35, 41) and 36% (95% CI 35, 37) in people with type 1, type 2 and without diabetes, respectively. In comparison with absence of diabetes, type 1 diabetes was associated with a higher incidence of ICH (1.74, 95% CI 1.38‐2.21) and higher case fatality after ICH (1.35, 95% CI 1.01‐1.70), after adjustment for age, sex and SES . The small increases in ICH incidence (1.06, 95% CI 0.99‐1.12) and case‐fatality (1.04, 95% CI 0.96‐1.13) in people with type 2 diabetes compared with people without diabetes were not statistically significant.