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Managing coeliac disease in patients with diabetes
Author(s) -
Leonard M. M.,
Cureton P. A.,
Fasano A.
Publication year - 2015
Publication title -
diabetes, obesity and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.445
H-Index - 128
eISSN - 1463-1326
pISSN - 1462-8902
DOI - 10.1111/dom.12310
Subject(s) - coeliac disease , medicine , gluten , type 1 diabetes , disease , type 2 diabetes , diabetes mellitus , autoimmunity , gluten free , pathogenesis , immunology , endocrinology , pathology
The association between coeliac disease and type 1 diabetes has long been established. The combination of genetic susceptibility along with a potential role for gluten in the pathogenesis of autoimmunity makes defining gluten's role in type 1 diabetes extremely important. Evidence supporting the role of a gluten‐free diet to improve complications associated with type 1 diabetes is not robust. However there is evidence to support improved growth, bone density and potentially the prevention of additional autoimmune diseases in patients with coeliac disease and type 1 diabetes. The gluten free diet is expensive and challenging to adhere to in people already on a modified diet. Early identification of those who have coeliac disease and would benefit from a gluten‐free diet is of utmost importance to prevent complications associated with type 1 diabetes and coeliac disease.