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Remission of diabetes in patients with long‐standing type 2 diabetes following placement of adjustable gastric band: a retrospective case control study
Author(s) -
Keogh J. B.,
Turner K. M.,
McDonald F.,
Toouli J.,
Clifton P. M.
Publication year - 2013
Publication title -
diabetes, obesity and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.445
H-Index - 128
eISSN - 1463-1326
pISSN - 1462-8902
DOI - 10.1111/dom.12034
Subject(s) - medicine , diabetes mellitus , type 2 diabetes , retrospective cohort study , body mass index , surgery , gastroenterology , endocrinology
Rates of remission in obese patients with long‐standing type 2 diabetes (>2 years), following an adjustable gastric band are unclear. We conducted a retrospective case–control study of patients (n = 89) matched for age and body mass index with non‐surgical controls. Cases had a longer duration of diabetes (99 ± 53 and 80 ± 59 months, p < 0.05) and a lower HbA1c than controls (7.9 ± 1.6 vs. 8.5 ± 1.9%, p < 0.05). At follow‐up (median 105 weeks) cases had lost 16.8 ± 13.5 kg and controls 1.7 ± 8.9 kg (p < 0.001) and HbA1c decreased by 0.6–0.8% (p < 0.001 for time) with no difference between cases and controls. Diabetes resolution, defined by HbA1c less than 6.5% and taking no medications, occurred in 14 (16%) cases and 2 controls. This is in contrast to published outcomes of resolution of type 2 diabetes after bariatric surgery. We conclude that there is a clear need for randomized studies of the effect of gastric banding in patients with long‐standing type 2 diabetes.