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Insulin Action
Author(s) -
S. H. BATES
Publication year - 1999
Publication title -
diabetic medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.474
H-Index - 145
eISSN - 1464-5491
pISSN - 0742-3071
DOI - 10.1111/dme.1999.16.s1.74
Subject(s) - medicine , citation , action (physics) , library science , quantum mechanics , physics , computer science
D-pinitol (3-0-methyl chiroinositol), an active principle of the traditional antidiabetic plant Bougainvillea spectabilis. is claimed to exert insulin mimetic effects. This was investigated in severely hyperglycaemic (about 20mM) insulin requiring streptozotocin-diabetic mice. D-pinitol (5, 10 and IOOmg/kg, po) acutely (0-6h) decreased the hyperglycaemia in a dose-related manner (lOOmglkg Dpinitol decreased blood glucose by about 15% p