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The Type 1 diabetes ‘honeymoon’ period is five times longer in men who exercise: a case–control study
Author(s) -
Chetan M. R.,
Charlton M. H.,
Thompson C.,
Dias R. P.,
Andrews R. C.,
Narendran P.
Publication year - 2019
Publication title -
diabetic medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.474
H-Index - 145
eISSN - 1464-5491
pISSN - 0742-3071
DOI - 10.1111/dme.13802
Subject(s) - medicine , honeymoon , type 2 diabetes , diabetes mellitus , table (database) , period (music) , control (management) , physical therapy , gerontology , demography , endocrinology , data mining , sociology , political science , computer science , law , physics , management , acoustics , economics
Type 1 diabetes mellitus is an autoimmune disorder characterized by the destruction of insulin-secreting β cells, and subsequent insulin deficiency. Shortly after diagnosis, 60% of adults with Type 1 diabetes experience a period of partial remission, or 'honeymoon' period, characterized by low insulin requirement and good glycaemic control [1]. Historically, the honeymoon period was defined as an insulin requirement of ≤ 0.5 units/kg/day together with HbA ≤ 58 mmol/mol (7.5%). Currently, the honeymoon period is defined as insulin dose-adjusted A (IDAA ) ≤ 9, where IDAA = HbA (%) + [4× insulin dose (units/kg/day)] [2]. This shows good correlation with stimulated C-peptide, and therefore endogenous insulin secretion [2]. This article is protected by copyright. All rights reserved.