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Men across a range of ethnicities have a higher prevalence of diabetes: findings from a cross‐sectional study of 500 000 UK Biobank participants
Author(s) -
Ferguson L. D.,
Ntuk U. E.,
CelisMorales C.,
Mackay D. F.,
Pell J. P.,
Gill J. M. R.,
Sattar N.
Publication year - 2018
Publication title -
diabetic medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.474
H-Index - 145
eISSN - 1464-5491
pISSN - 0742-3071
DOI - 10.1111/dme.13551
Subject(s) - medicine , ethnic group , cross sectional study , demography , diabetes mellitus , biobank , type 2 diabetes , gerontology , endocrinology , pathology , sociology , biology , anthropology , genetics
Aims Studies show that white men have a higher prevalence of Type 2 diabetes mellitus than women at a given age and BMI , but equivalent standardized data for other ethnic groups in the UK are sparse. Methods This cross‐sectional study analysed UK Biobank data from 489 079 participants to compare the prevalence of diabetes mellitus across four major ethnic groups including: 471 700 (96.4%) white, 7871 (1.6%) South Asian, 7974 (1.6%) black and 1534 (0.3%) Chinese participants, before and after standardizing for age, socio‐economic status ( SES ), BMI and lifestyle factors including physical activity, TV viewing, fruit and vegetable intake, processed meat, red meat, oily fish, alcohol intake and smoking. A subgroup analysis of South Asians was also undertaken. Results Crude diabetes prevalence was higher in men across all four ethnicities. After standardizing for age, SES , BMI and lifestyle factors, a significant sex difference in diabetes prevalence persisted in white (men 6.0% vs. women 3.6%), South Asian (21.0% vs. 13.8%) and black individuals (13.3% vs. 9.7%) ( P < 0.0001); there was a non‐significant difference between Chinese men and women (7.1% vs. 5.5%) ( P = 0.211). Sex differences persisted across South Asian subgroups. Conclusions Men across a range of major ethnic groups including white, South Asian and black, have a higher prevalence of diabetes compared with women of similar age, BMI , SES and lifestyle in the UK .