Ovarian reserve in women with Type 1 diabetes in the Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications Study | Zendy

Kim C. | Zendy; Dunn R. L. | Zendy; Braffett B. | Zendy; Cleary P. A. | Zendy; Arends V. | Zendy; Steffes M. | Zendy; Lanham M. S. M. | Zendy; Randolph J. F. | Zendy; Wessells H. | Zendy; Wellons M. F. | Zendy; Sarma A. V. | Zendy

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Ovarian reserve in women with Type 1 diabetes in the Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications Study

Author(s) -

Kim C.,

Dunn R. L.,

Braffett B.,

Cleary P. A.,

Arends V.,

Steffes M.,

Lanham M. S. M.,

Randolph J. F.,

Wessells H.,

Wellons M. F.,

Sarma A. V.

Publication year - 2016

Publication title -

diabetic medicine

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.474

H-Index - 145

eISSN - 1464-5491

pISSN - 0742-3071

DOI - 10.1111/dme.13072

Subject(s) - medicine , obstetrics and gynaecology , biostatistics , epidemiology , diabetes mellitus , psychological intervention , family medicine , gerontology , gynecology , nursing , pregnancy , endocrinology , genetics , biology

Markers of ovarian reserve such as anti-Müllerian hormone (AMH) are used in the management of fertility and prediction of menopause. Although women with type 1 diabetes have a high prevalence of reproductive disorders, no studies have examined whether markers of ovarian reserve are associated with randomization to intensive insulin therapy and subsequent markers of glycemic control. Using data from the Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications Study, we found that the strongest predictor of AMH was chronologic age, and that diabetes-specific variables such as randomization to intensive therapy, insulin dose, and glycemic control were not associated with AMH concentrations. This article is protected by copyright. All rights reserved.

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