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Dairy consumption and risk of metabolic syndrome: a meta‐analysis
Author(s) -
Kim Y.,
Je Y.
Publication year - 2016
Publication title -
diabetic medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.474
H-Index - 145
eISSN - 1464-5491
pISSN - 0742-3071
DOI - 10.1111/dme.12970
Subject(s) - medicine , meta analysis , relative risk , metabolic syndrome , prospective cohort study , confounding , cohort study , incidence (geometry) , epidemiology , cohort , lower risk , environmental health , confidence interval , obesity , physics , optics
Aims To conduct a systematic review and meta‐analysis of epidemiological studies in order to assess quantitatively the effect of dairy consumption on risk of metabolic syndrome. Methods We searched for eligible studies published up to March 2015 through the PubMed and Embase databases and reviewed the references of relevant articles. Random‐effects models were used to calculate the pooled relative risks with 95% CI s after adjusting for several confounders. Results We identified nine prospective cohort studies including a total of 35 379 subjects and 7322 incident cases of metabolic syndrome, and 12 cross‐sectional studies including 37 706 subjects. In the meta‐analysis of prospective cohort studies, the pooled relative risk of incidence of metabolic syndrome for the highest vs. the lowest category of dairy consumption was 0.85 (95% CI 0.73–0.98), and for a 1‐serving/day increment of dairy consumption, the pooled relative risk was 0.88 (95% CI 0.82–0.95). In the meta‐analysis of cross‐sectional studies, the pooled relative risk of prevalence of metabolic syndrome for the highest vs. the lowest category of dairy consumption was 0.73 (95% CI 0.63–0.86). The association was not significantly different by geographical region, follow‐up time and adjustment factors. Conclusion Our findings indicate that dairy consumption is inversely associated with the incidence and prevalence of metabolic syndrome. Further well‐designed cohort studies and randomized controlled trials are warranted to provide definitive evidence.