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Metabolic syndrome of weight change from pre‐pregnancy to 1–5 years post‐partum among Chinese women with prior gestational diabetes
Author(s) -
Li W.,
Liu H.,
Qiao Y.,
Lv F.,
Zhang S.,
Wang L.,
Leng J.,
Liu H.,
Qi L.,
Tuomilehto J.,
Hu G.
Publication year - 2015
Publication title -
diabetic medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.474
H-Index - 145
eISSN - 1464-5491
pISSN - 0742-3071
DOI - 10.1111/dme.12790
Subject(s) - medicine , pregnancy , weight gain , gestational diabetes , overweight , obstetrics , metabolic syndrome , weight change , diabetes mellitus , obesity , body mass index , gestation , weight loss , endocrinology , body weight , genetics , biology
Abstract Aims Few studies have evaluated the effect of weight change from pre‐pregnancy to post‐partum with the risk of cardiometabolic diseases among women with a history of gestational diabetes mellitus. The aim of this study was to evaluate the association between weight change from pre‐pregnancy to 1–5 years post‐partum with metabolic syndrome among Chinese women with prior gestational diabetes mellitus. Methods We performed a retrospective cohort study in 1263 women with gestational diabetes mellitus at 1–5 years post‐partum. Participants were divided into four groups based on their weight change from pre‐pregnancy to 1–5 years post‐partum: loss of ≥ 3 kg, ± 3 kg, gain of 3–7 kg and gain of ≥7 kg. Results The prevalence of metabolic syndrome was 12.1%, 16.2%, 26.0% and 44.3% among women with weight loss ≥ 3 kg, stable weight ( ± 3 kg), weight gain 3–7 kg and weight gain ≥ 7 kg from pre‐pregnancy to post‐partum, respectively. The positive association between weight change and metabolic syndrome was observed among women with pre‐pregnancy normal weight ( BMI < 24 kg/m 2 ), overweight ( BMI 24–27.9 kg/m 2 ) and obesity ( BMI ≥ 28 kg/m 2 ). The prevalence of metabolic syndrome was almost similar among pre‐pregnancy normal weight women with weight gain ≥ 7 kg, pre‐pregnancy overweight women with stable weight ( ± 3 kg) and pre‐pregnancy obese women with weight loss ≥ 3 kg from pre‐pregnancy to post‐partum ( P = 0.62). Conclusions Women with gestational diabetes mellitus who had large weight gain from pre‐pregnancy to post‐partum were more likely to develop metabolic syndrome. Women who are pre‐pregnancy overweight/obesity and also diagnosed as gestational diabetes mellitus during pregnancy need more weight control after delivery.