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The impact of diabetes‐related complications on healthcare costs: new results from the UKPDS (UKPDS 84)
Author(s) -
Alva M. L.,
Gray A.,
Mihaylova B.,
Leal J.,
Holman R. R.
Publication year - 2015
Publication title -
diabetic medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.474
H-Index - 145
eISSN - 1464-5491
pISSN - 0742-3071
DOI - 10.1111/dme.12647
Subject(s) - medicine , myocardial infarction , stroke (engine) , diabetes mellitus , heart failure , emergency medicine , amputation , surgery , mechanical engineering , engineering , endocrinology
Aims To estimate the immediate and long‐term inpatient and non‐inpatient costs for Type 2 diabetes‐related complications. Methods The costs of all consultations, visits, admissions and procedures associated with diabetes‐related complications during UK Prospective Diabetes Study post‐trial monitoring in the period 1997–2007 were estimated using hospitalization records for 2791 patients in England and resource use questionnaires that were administered to 3589 patients across the UK . Results The estimated (95% CI ) inpatient care costs (in 2012 pounds sterling) in the event year for the example of a 60‐year‐old man were: non‐fatal ischaemic heart disease £9767 (£7038–£12 696); amputation £9546 (£6416–£13 463); non‐fatal stroke £6805 (£3856–£10 278); non‐fatal myocardial infarction £6379 (£4290–£8339); fatal stroke £3954 (£2012–£6428); fatal ischaemic heart disease £3766 (£746–£5512); heart failure £3191 (£1678–4903); fatal myocardial infarction £1521 (£647–£2670); and blindness in one eye £1355 (£415–£2655). In subsequent years, estimated (95% CI ) costs ranged from £1792 (£1060–£2943) for amputations to £453 (£315–£691) for blindness in one eye. Costs of non‐inpatient healthcare in the event year were: amputation £2699 (£1409–£4126); blindness in one eye £1790 (£878–£3056); non‐fatal stroke £1019 (£770–£1499); nonfatal myocardial infarction £1963 (£794–£1157); heart failure £979 (£708–£1344); non‐fatal ischaemic heart disease £864 (£718–£1014); and cataract extraction £700 (£619–£780). In each subsequent year, non‐inpatient costs ranged from £1611 (£1193–£2116) for amputations to £654 (£572–£799) for ischaemic heart disease. Conclusions Diabetic complications are associated with substantial immediate and long‐term healthcare costs. Our comprehensive new estimates of these costs, derived from detailed recent UK Prospective Diabetes Study post‐trial data, should aid researchers and health policy analyses.