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Erectile dysfunction is a strong predictor of poor quality of life in men with Type 2 diabetes mellitus
Author(s) -
Malavige L. S.,
Jayaratne S. D.,
Kathriarachchi S. T.,
Sivayogan S.,
Ranasinghe P.,
Levy J. C.
Publication year - 2014
Publication title -
diabetic medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.474
H-Index - 145
eISSN - 1464-5491
pISSN - 0742-3071
DOI - 10.1111/dme.12412
Subject(s) - medicine , erectile dysfunction , quality of life (healthcare) , libido , cross sectional study , diabetes mellitus , sexual dysfunction , premature ejaculation , bayesian multivariate linear regression , endocrinology , linear regression , pathology , psychology , machine learning , computer science , psychoanalysis , nursing
Aims To identify predictors of poor quality of life among men with diabetes from a comprehensive set of sexual, clinical, socio‐economic and lifestyle variables. Methods This was a cross‐sectional observational‐study of 253 men with Type 2 diabetes, randomly selected from a clinic in Colombo, Sri Lanka. Erectile dysfunction was assessed using the five‐item International Index of Erectile Function and quality of life was assessed using the Sri Lankan version of the 36‐item short form health survey questionnaire and the disease‐specific Psychological Impact of Erectile Dysfunction scale. The presence of premature ejaculation, reduced libido, socio‐demographic and lifestyle data was obtained using an interviewer‐administered questionnaire. Significant predictors of quality of life were identified by stepwise multivariate linear regression models for short form‐36 subscales, summary scales and two scales of Psychological Impact of Erectile Dysfunction. Results Significant predictors on the physical summary scale of the 36‐item short form were erectile dysfunction (β = 7.93, 95% CI 3.70–12.17, P < 0.001) and reduced libido (β = 5.20, 95% CI 0.82–9.59, P < 0.05). Predictors on the mental health summary scale of the 36‐item short form were erectile dysfunction (β = 5.82, 95% CI 2.26–9.37, P < 0.01), BMI > 27.5 kg/m 2 (β = 9.12, 95% CI 1.38–17.44, P < 0.05), ischaemic heart disease (β = 6.39, 95% CI 0.74–12.04, P < 0.05) and insulin therapy (β = 5.28, 95% CI 0.34–10.22, P < 0.05). Significant predictors in the sexual experience scale of the Psychological Impact of Erectile Dysfunction were erectile dysfunction (β = 6.57, 95% CI 4.63–8.51, P < 0.001), reduced libido (β =4.33, 95% CI 2.34–6.32, P < 0.001) and postural hypotension (β = 3.99, 95% CI 0.13–7.85, P < 0.05). Predictors on the emotional life scale of the Psychological Impact of Erectile Dysfunction were erectile dysfunction (β = 2.96, 95% CI 1.37–4.58, P < 0.001), reduced libido 2.75 (β = 2.75, 95% CI 1.12–4.40, P < 0.01), younger age (β = 1.05, 95% CI 0.35–1.75, P < 0.01) and postural hypotension (β = 3.39, 95% CI 0.35–6.45, P < 0.05). Conclusion Erectile dysfunction was a strong predictor of poor generic and disease‐specific quality of life among other sexual and clinical variables in men with diabetes.