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The burden of diabetes mellitus and impaired fasting glucose in an urban population of Sri Lanka
Author(s) -
Pinidiyapathirage M. J.,
Kasturiratne A.,
Ranawaka U. K.,
Gunasekara D.,
Wijekoon N.,
Medagoda K.,
Perera S.,
Takeuchi F.,
Kato N.,
Warnakulasuriya T.,
Wickremasinghe A. R.
Publication year - 2013
Publication title -
diabetic medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.474
H-Index - 145
eISSN - 1464-5491
pISSN - 0742-3071
DOI - 10.1111/dme.12013
Subject(s) - medicine , diabetes mellitus , waist , population , impaired fasting glucose , blood pressure , cross sectional study , fasting glucose , body mass index , waist–hip ratio , endocrinology , impaired glucose tolerance , type 2 diabetes , environmental health , insulin resistance , pathology
Aims To describe the burden of diabetes mellitus and impaired fasting glucose in middle‐aged residents (35–64 years) in an urban area of Sri Lanka. Methods A cross‐sectional survey was conducted in the Ragama Medical Officer of Health area, from which 2986 participants (1349 men and 1637 women) were randomly selected from the electoral registry between January and December 2007. The participants underwent a physical examination and had their height, weight, waist and hip circumferences and blood pressure measured by trained personnel. Fasting blood samples were taken for measurement of glucose, HbA 1c and lipids. The prevalence of diabetes (fasting plasma glucose > 7 mmol/l) and impaired fasting glycaemia (fasting plasma glucose 5.6–6.9 mmol/l) and major predictors of diabetes in Sri Lanka were estimated from the population‐based data. Results Age‐adjusted prevalence of diabetes mellitus in this urban population was 20.3% in men and 19.8% in women. Through the present screening, 263 patients with diabetes and 1262 with impaired fasting glucose levels were identified. The prevalence of newly detected diabetes was 35.7% of all patients with diabetes. Among patients with diabetes, only 23.8% were optimally controlled. In the regression models, high BMI , high waist circumference, high blood pressure and hypercholesterolaemia increased the fasting plasma glucose concentration, independent of age, sex and a family history of diabetes. Conclusions Our data demonstrate the heavy burden of diabetes in this urban population. Short‐ and long‐term control strategies are required, not only for optimal therapy among those affected, but also for nationwide primary prevention of diabetes.