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Skeletal muscle fiber type‐specific succinate dehydrogenase activity is not reduced in children with cerebral palsy
Author(s) -
S DAYANIDHI,
A ZOGBY,
H CHAMBERS,
SCHENK
Publication year - 2015
Publication title -
developmental medicine and child neurology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.658
H-Index - 143
eISSN - 1469-8749
pISSN - 0012-1622
DOI - 10.1111/dmcn.14_12886
Subject(s) - succinate dehydrogenase , cerebral palsy , skeletal muscle , fiber , medicine , fiber type , chemistry , endocrinology , neuroscience , biochemistry , physical medicine and rehabilitation , psychology , enzyme , organic chemistry
groups showed that of those who did not receive SDR, 26% reported improved motor functioning, 38% reported no change in motor functioning, and 36% reported worse motor functioning. In contrast, of those who did receive SDR, 62% reported improved motor functioning, 28% reported no change in motor functioning, and just 10% reported worse motor functioning. Conclusions/Significance: Adults with cerebral palsy who had a selective dorsal rhizotomy as a child reported significantly less fatigue, higher function, and better change in overall motor function over time compared to similarly aged peers who had not had the surgery. Those who had SDR also had marginally lower pain severity. This suggests that symptomatic and functional benefits of SDR persist even long after the surgery.