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Core outcome set for children with neurological impairment and tube feeding
Author(s) -
Joachim Kariym C,
FaridKapadia Mufiza,
Butcher Nancy J,
Cheeatow Alyssandra,
Monsour Andrea,
Cohen Eyal,
Mahant Sanjay,
Guttmann Astrid,
Offringa Martin
Publication year - 2020
Publication title -
developmental medicine and child neurology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.658
H-Index - 143
eISSN - 1469-8749
pISSN - 0012-1622
DOI - 10.1111/dmcn.14326
Subject(s) - likert scale , medicine , health care , gastrostomy , psychology , physical therapy , pediatrics , family medicine , surgery , developmental psychology , economics , economic growth
Aim To develop a core outcome set (COS) for evaluating gastrostomy/gastrojejunostomy tube impact in children with neurological impairment. Method Healthcare providers/researchers and caregivers rated the importance of candidate outcomes on a 5‐point Likert scale. Outcomes rated ‘somewhat important’ or ‘very important’ by most (≥85%) respondents were voted on during a consensus meeting. Outcomes that reached consensus for inclusion were ratified and assigned to Outcome Measures in Rheumatology filter core areas. The COS was validated in a separate group of caregivers. Results Twelve outcomes were selected from 120 candidate outcomes to form the COS. These included five ‘Life Impact’ outcomes, three ‘Pathophysiological Manifestations’ outcomes, two ‘Resource Use’ outcomes, one ‘Growth and Development’ outcome, and one ‘Death’ outcome. Interpretation We developed an evidence‐informed and consensus‐based COS for use in studies of gastrostomy/gastrojejunostomy tube feeding in children with neurological impairment. Implementation of this COS will help reduce heterogeneity between studies and facilitate evidence‐based decision‐making. What the paper adds Caregivers, healthcare providers, and researchers ranked the importance of 120 outcomes. Twelve core outcomes were identified as essential to measure in future clinical research studies.

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