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Issue Information
Publication year - 2017
Publication title -
development, growth and differentiation
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 0.864
H-Index - 66
eISSN - 1440-169X
pISSN - 0012-1592
DOI - 10.1111/dgd.12316
Subject(s) - epiblast , cover (algebra) , endoderm , x inactivation , genetics , biology , chromosome , genomic imprinting , x chromosome , embryo , dna methylation , embryonic stem cell , embryogenesis , gene , gastrulation , gene expression , mechanical engineering , engineering
Cover Photograph: Live‐cell fl uorescence imaging to show X chromosome inactivation (XCI) at an E6.25 mouse embryo. Green and red show maternally and paternally derived X chromosome, respectively. Either the maternally or paternally derived X chromosomes begin to be silenced randomly in the epiblast. However, in the visceral endoderm and extraembryonic ectoderm, the paternal X chromosome is inactivated selectively by imprinted XCI, and only the maternal X chromosome (green) is active (See Kobayashi pp. 493–500).