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Multiple roles of Equarin during lens development
Author(s) -
Song Xiaohong,
Tanaka Hideaki,
Ohta Kunimasa
Publication year - 2014
Publication title -
development, growth and differentiation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.864
H-Index - 66
eISSN - 1440-169X
pISSN - 0012-1592
DOI - 10.1111/dgd.12121
Subject(s) - lens (geology) , through the lens metering , identification (biology) , biology , variety (cybernetics) , development (topology) , eye development , computational biology , neuroscience , gene , cognitive science , computer science , psychology , genetics , transcription factor , artificial intelligence , paleontology , botany , mathematical analysis , mathematics
Since the days of Hans Spemann, the ocular lens has served as one of the most important developmental systems for elucidating the fundamental processes of induction and differentiation. Lens is an important source of signals that influence the eye development and a variety of genes expressed by the lens have been identified. The identification of additional molecule(s), especially secreted ones that might mediate signals, will extend our knowledge of the molecular mechanisms of eye and lens development. Here, we will introduce a soluble molecule, Equarin, and discuss its vital role in multiple aspects of lens development.