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Pluripotent genes in avian stem cells
Author(s) -
Jean Christian,
Aubel Pauline,
Soleihavoup Clément,
Bouhallier Frantz,
Voisin Sophie,
Lavial Fabrice,
Pain Bertrand
Publication year - 2013
Publication title -
development, growth and differentiation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.864
H-Index - 66
eISSN - 1440-169X
pISSN - 0012-1592
DOI - 10.1111/dgd.12021
Subject(s) - homeobox protein nanog , sox2 , epiblast , biology , induced pluripotent stem cell , embryonic stem cell , stem cell , blastocyst , kosr , rex1 , inner cell mass , microbiology and biotechnology , embryo , embryoid body , genetics , gene , embryogenesis , gastrulation
Embryonic stem ( ES ) cells were first isolated in 1981 in the mouse from the in vitro proliferation of the inner cell mass of a 3.5 days post‐coitum (dpc) blastocyst. Later on, epiblast stem cells (Epi SC ) were identified from in vitro culture of the epiblast of a 6.5 dpc mouse embryo, leading to the concept of naïve and primed stem cells. Among non‐mammalian species, ES cells have been characterized both in birds and fish; here, we focus on cells derived from chicken and the pluripotent associated markers such as OCT 4, SOX 2, NANOG , and KLF , previously identified in mammalian cells. In this review, we present both published and original data regarding the involvement of those pluripotent associated genes in the ES cells and early embryo of chicken.