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Endoclip papillaplasty restores sphincter of Oddi function: Pilot study
Author(s) -
Yan Xiue,
Zheng Wei,
Zhang Yaopeng,
Chang Hong,
Wang Kun,
Li Xin,
Zhang Hejun,
Wang Yingchun,
Yao Wei,
Li Ke,
Huang Yonghui
Publication year - 2021
Publication title -
digestive endoscopy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.5
H-Index - 56
eISSN - 1443-1661
pISSN - 0915-5635
DOI - 10.1111/den.13887
Subject(s) - medicine , sphincter of oddi , sphincter of oddi dysfunction , sphincter , surgery , general surgery
Objectives Endoscopic sphincterotomy (EST) damaged the sphincter of Oddi (SO) function. This study aimed to explore the feasibility and efficacy of endoclip papillaplasty in restoring SO function. Methods This prospective pilot study included consecutive patients with choledocholithiasis (stone size ≥10 mm) who underwent large‐EST for stone removal, followed by endoclip papillaplasty, between May 2018 and March 2019. Results Thirty patients were enrolled in this trail. Overall, 80% of the patients had a SO basal pressure of >10 mmHg after endoclip papillaplasty. Manometric parameters, including SO basal pressure, phasic wave contraction amplitude, phasic waves per minute, recovered after endoclip papillaplasty ( P > 0.05). There were no significant differences in the manometric parameters of SO between healing grades A and B. Six patients developed mild post‐endoscopic retrograde cholangiopancreatography pancreatitis, including three that had pancreatic stenting. Bile duct stone recurrence developed in 3.3% of the patients (1/30) during an 18‐month follow‐up. Conclusions Endoclip papillaplasty might restore SO function and possibly prevented biliary stone and cholangitis recurrence.