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Diagnostic performance of endoscopic ultrasonography‐guided elastography for solid pancreatic lesions: Shear‐wave measurements versus strain elastography with histogram analysis
Author(s) -
Ohno Eizaburo,
Kawashima Hiroki,
Ishikawa Takuya,
Iida Tadashi,
Suzuki Hirotaka,
Uetsuki Kota,
Yashika Jun,
Yamada Kenta,
Yoshikawa Masakatsu,
Gibo Noriaki,
Aoki Toshinori,
Kataoka Kunio,
Mori Hiroshi,
Yamamura Takeshi,
Furukawa Kazuhiro,
Nakamura Masanao,
Hirooka Yoshiki,
Fujishiro Mitsuhiro
Publication year - 2021
Publication title -
digestive endoscopy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.5
H-Index - 56
eISSN - 1443-1661
pISSN - 0915-5635
DOI - 10.1111/den.13791
Subject(s) - medicine , elastography , radiology , ultrasonography , endoscopic ultrasonography , histogram , strain (injury) , endoscopy , ultrasound , artificial intelligence , computer science , image (mathematics)
Background and aims Endoscopic ultrasound (EUS) elastography (EUS‐EG) is a minimally invasive diagnostic method for evaluating tissue elasticity. The aim of this study was to evaluate the feasibility of newly developed EUS shear‐wave measurement (EUS‐SWM) and to compare diagnostic performance between EUS‐SWM and the conventional strain elastography (SE) for the measurement of elasticity of solid pancreatic lesions (SPLs). Methods From December 2017 until August 2019, we retrospectively reviewed 64 consecutive cases with SPLs who underwent both EUS‐SWM and SE. EUS‐SWM was used to measure the shear‐wave velocity, Vs (m/s), and the unique measurement reliability index, VsN (%), in the target lesion. SE images were assessed by strain histogram (SH) analysis, and the mean strain value of the elasticity index was measured. We evaluated the diagnostic performance of EUS‐SWM and SE with SH to characterize the SPLs. Results The Vs (m/s) values of SPLs were 2.19 for pancreatic cancer (PC), 1.31 for pancreatic neuroendocrine neoplasm (PanNEN), 2.56 for mass‐forming pancreatitis (MFP) and 1.58 for metastatic tumors. Vs showed no significant difference based on the disease. The mean strain values were 45.5 for PC, 47.3 for PanNEN, and 74.5 for MFP. In the comparison of tissue elasticity between PC and MFP, Vs showed no significant difference ( P = 0.5687); however, the mean strain value was significantly lower in PC cases (45.4 vs 74.5: P = 0.0007). Conclusion Endoscopic ultrasound SWM tended to be unstable for the measurement of elasticity of SPLs, and conventional SE with SH was superior for their characterization.