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Clinical value of capsule endoscopy for detecting small bowel lesions in patients with intestinal Behçet's disease
Author(s) -
Arimoto Jun,
Endo Hiroki,
Kato Takayuki,
Umezawa Shotaro,
Fuyuki Akiko,
Uchiyama Shiori,
Higurashi Takuma,
Ohkubo Hidenori,
aka Takashi,
Takeno Mitsuhiro,
Ishigatsubo Yoshiaki,
Sakai Eiji,
Matsuhashi Nobuyuki,
Nakajima Atsushi
Publication year - 2016
Publication title -
digestive endoscopy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.5
H-Index - 56
eISSN - 1443-1661
pISSN - 0915-5635
DOI - 10.1111/den.12552
Subject(s) - medicine , capsule endoscopy , gastroenterology , behcet's disease , colonoscopy , endoscopy , capsule , crohn's disease , disease , colorectal cancer , cancer , botany , biology
Background and Aim To evaluate the clinical value of capsule endoscopy (CE) in patients with intestinal Behçet's disease (BD). Methods The present study was a case–control pilot study conducted in intestinal BD patients and healthy volunteers. A total of 19 patients with intestinal BD (intestinal BD group) and 19 healthy volunteers (control group) matched for age and sex were enrolled. Frequency, number of small bowel lesions per subject, and Lewis score were comparatively evaluated between the two groups. Results Of the 19 patients with intestinal BD, 18 (94.7%) had reddened lesions, 15 (78.9%) had erosions, and nine (47.4%) had ulcers. There were significant differences in the frequency of reddened lesions ( P < 0.0001), erosions ( P < 0.0001) and ulcers ( P = 0.0011) between the two groups. The difference in the number of small bowel lesions between the two groups was also statistically significant. The median Lewis score in the intestinal BD group was significantly higher than that in the control group (intestinal BD group 237 (0–768) vs control group 8 (0–135); P < 0.0001). Analysis according to the location in the small bowel revealed that the frequency of ulcers tended to increase towards the distal intestine. Conclusion This is the first CE study conducted to examine small bowel involvement in intestinal BD patients. Our results suggest that CE evaluation is necessary, in addition to colonoscopy, in all intestinal BD patients.