Premium
Skin disorders in diabetes mellitus
Author(s) -
Gkogkolou Paraskevi,
Böhm Markus
Publication year - 2014
Publication title -
jddg: journal der deutschen dermatologischen gesellschaft
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.463
H-Index - 60
eISSN - 1610-0387
pISSN - 1610-0379
DOI - 10.1111/ddg.12424
Subject(s) - diabetes mellitus , medicine , diabetic foot , pathophysiology , type 2 diabetes mellitus , intensive care medicine , organ system , disease , endocrinology
Summary Diabetes mellitus is one of the most common diseases in industrialized Western countries with about 300 million affected patients worldwide. The hyperglycemic state of diabetes mellitus leads to changes in almost every human cell type and organ. Skin changes are considered the most common manifestations of diabetes mellitus. As skin changes can manifest before onset of diabetes mellitus, they may have a diagnostic relevance. Other cutaneous manifestations develop during the course of diabetes mellitus and may be associated with complications in internal organs or may occur as an adverse effect of antidiabetic therapy. In particular, the presence of the diabetic foot syndrome is associated with significantly increased morbidity and mortality of diabetes patients as well as with markedly elevated direct and indirect costs for the health care system. In this article the most common skin diseases of patients with diabetes mellitus as well as their pathophysiology and current treatment are reviewed.