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Combined large cell neuroendocrine carcinoma and spindle cell carcinoma of the lung: Report of a rare entity presenting in fine needle aspiration
Author(s) -
Grosse Alexandra,
Grosse Claudia
Publication year - 2021
Publication title -
cytopathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.512
H-Index - 48
eISSN - 1365-2303
pISSN - 0956-5507
DOI - 10.1111/cyt.12888
Subject(s) - medicine , pathology , carcinoma , lung , cell , spindle cell carcinoma , large cell , small cell lung carcinoma , neuroendocrine carcinoma , neuroendocrine tumors , small cell carcinoma , adenocarcinoma , biology , cancer , genetics
This report for the first time describes the cytological findings of combined large cell neuroendocrine carcinoma (LCNEC) and spindle cell carcinoma of the lung, a rare combined variant of large cell neuroendocrine carcinoma. This entity is identified in FNAC by the characteristic finding of a dual cell population with distinct features of LCNEC and spindle cell/giant cell carcinoma.