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Identification of two independent clones underlying the co‐existence of myelodysplastic syndrome with excess of blasts type 2 and isolated 5q‐ and smouldering multiple myeloma
Author(s) -
Quintini Martina,
Arniani Silvia,
Ascani Stefano,
Camerini Chiara,
Crescenzi Barbara,
Di Battista Valeria,
Moretti Martina,
Pellanera Fabrizia,
Pierini Valentina,
Mecucci Cristina
Publication year - 2020
Publication title -
cytopathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.512
H-Index - 48
eISSN - 1365-2303
pISSN - 0956-5507
DOI - 10.1111/cyt.12752
Subject(s) - multiple myeloma , monosomy , medicine , myelodysplastic syndromes , identification (biology) , cancer research , genetics , gene , bone marrow , karyotype , biology , chromosome , botany
This report is dealing with simultaneous diagnosis of Myelodysplastic Syndrome with Excess of Blasts 2 ( MDS ‐ EB 2) with isolated 5q deletion and Smoldering Multiple Myeloma ( SMM ) with typical changes, namely t (4;14) and monosomy 13. I‐ FISH and FICTION techniques showed distinct specific clones underlie the two hematological malignancies.