Synovial sarcoma diagnosis on fine needle cytology sample confirmed by fluorescence in situ hybridisation | Zendy

Ronchi Andrea | Zendy; Panarese Iacopo | Zendy; Aquino Gabriella | Zendy; Gambardella Antonio | Zendy; Franco Renato | Zendy; Cozzolino Immacolata | Zendy

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Synovial sarcoma diagnosis on fine needle cytology sample confirmed by fluorescence in situ hybridisation

Author(s) -

Ronchi Andrea,

Panarese Iacopo,

Aquino Gabriella,

Gambardella Antonio,

Franco Renato,

Cozzolino Immacolata

Publication year - 2019

Publication title -

cytopathology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.512

H-Index - 48

eISSN - 1365-2303

pISSN - 0956-5507

DOI - 10.1111/cyt.12651

Subject(s) - synovial sarcoma , medicine , sarcoma , in situ hybridisation , chromosomal translocation , cytology , pathology , fluorescence in situ hybridization , biology , immunohistochemistry , biochemistry , chromosome , gene

The cytological diagnosis of a monomorphic synovial sarcoma can be challenging, especially when it presents in a rare intramuscular location. As synovial sarcoma is characterized by the specific balanced chromosomal translocation t(X;18)(p11;q11), an integrated cytological and molecular approach is considered mandatory.

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