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Synovial sarcoma diagnosis on fine needle cytology sample confirmed by fluorescence in situ hybridisation
Author(s) -
Ronchi Andrea,
Panarese Iacopo,
Aquino Gabriella,
Gambardella Antonio,
Franco Renato,
Cozzolino Immacolata
Publication year - 2019
Publication title -
cytopathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.512
H-Index - 48
eISSN - 1365-2303
pISSN - 0956-5507
DOI - 10.1111/cyt.12651
Subject(s) - synovial sarcoma , medicine , sarcoma , in situ hybridisation , chromosomal translocation , cytology , pathology , fluorescence in situ hybridization , biology , immunohistochemistry , biochemistry , chromosome , gene
The cytological diagnosis of a monomorphic synovial sarcoma can be challenging, especially when it presents in a rare intramuscular location. As synovial sarcoma is characterized by the specific balanced chromosomal translocation t(X;18)(p11;q11), an integrated cytological and molecular approach is considered mandatory.