Premium
Reliability of reporting the presence of transformation zone material in Papanicolaou smears using an automated screening system
Author(s) -
Erbarut Seven I.,
Mollamemisoglu H.,
Eren F.
Publication year - 2017
Publication title -
cytopathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.512
H-Index - 48
eISSN - 1365-2303
pISSN - 0956-5507
DOI - 10.1111/cyt.12411
Subject(s) - papanicolaou stain , medicine , reliability (semiconductor) , papanicolaou test , cytology , gynecology , medical physics , obstetrics , pathology , cervical cancer , cancer , power (physics) , physics , quantum mechanics
Objective This study was conducted to evaluate the reliability of using an interactive automated screening system ( IAS ) to determine the presence of endocervical and/or metaplastic cells (transformation zone material; TZM ) in liquid‐based cytology ( LBC ) Papanicolaou (Pap) smear slides. Materials and methods A series of LBC Pap smears was manually screened to determine the presence or absence of TZM . The results were compared to those obtained through IAS . Results ThinPrep ® Imaging System (Imager)‐assisted screening indicated that 22.4% of the slides did not contain TZM in cases in which previous manual screening revealed that 100% of the slides did contain TZM . Conclusion The reliability of determining TZM through IAS is limited. Manual screening of the slides appears to be necessary to report the presence of TZM accurately.