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CSF cytology diagnosis of NRAS ‐mutated primary leptomeningeal melanomatosis with neurocutaneous melanosis
Author(s) -
Kolin D. L.,
Geddie W. R.,
Ko H. M.
Publication year - 2017
Publication title -
cytopathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.512
H-Index - 48
eISSN - 1365-2303
pISSN - 0956-5507
DOI - 10.1111/cyt.12366
Subject(s) - medicine , immunocytochemistry , neuroblastoma ras viral oncogene homolog , pathology , cytology , melanoma , cytopathology , cancer , cancer research , colorectal cancer , kras
Primary leptomeningeal melanomatosis is an extremely rare, diffuse, malignant melanocytic neoplasm without a localised mass. In this case, both immunocytochemistry and molecular testing were successfully completed using a CSF sample, allowing confirmation of the diagnosis and determination of the mutational status of the melanoma.