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Endobronchial ultrasound‐guided transbronchial needle aspiration: performance of biomedical scientists on rapid on‐site evaluation and preliminary diagnosis
Author(s) -
Schacht M. J.,
Toustrup C. B.,
Madsen L. B.,
Martiny M. S.,
Larsen B. B.,
Simonsen J. T.
Publication year - 2016
Publication title -
cytopathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.512
H-Index - 48
eISSN - 1365-2303
pISSN - 0956-5507
DOI - 10.1111/cyt.12338
Subject(s) - medicine , medical diagnosis , endobronchial ultrasound , cohen's kappa , kappa , medical physics , radiology , nuclear medicine , bronchoscopy , statistics , linguistics , philosophy , mathematics
Objectives Rapid on‐site evaluation ( ROSE ) of endobronchial ultrasound‐guided transbronchial needle aspiration ( EBUS ‐ TBNA ) followed by a subsequent preliminary adequacy assessment and a preliminary diagnosis, was performed at Aarhus University Hospital by biomedical scientists ( BMS ). The aim of this study was to evaluate the BMS accuracy of ROSE adequacy assessment, the preliminary adequacy assessment and the preliminary diagnosis as compared with the cytopathologist‐rendered final adequacy assessment and final diagnosis. Methods The BMS ‐rendered assessments for 717 sites from 319 consecutive patients over a 4‐month period were compared with the cytopathologist‐rendered assessments. Comparisons of adequacy and preliminary diagnoses were based on inter‐observer Cohen's Kappa coefficient with a 95% confidence interval ( CI ). Results Strong correlations between ROSE and final adequacy assessments [Kappa coefficient of 0.90 ( CI : 0.85–0.96)] and between the preliminary and final adequacy assessments [Kappa coefficient of 0.93 ( CI : 0.87–0.99)] were found. As for the correlation between the preliminary and final diagnoses, the Kappa coefficient was 0.99 ( CI : 0.98–1). Conclusion Both ROSE and preliminary adequacy assessments as well as preliminary diagnoses, all performed by BMS , were highly accurate when compared with the final assessment by the cytopathologist.