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A case of lymphomatoid papulosis type E in a young adult: An uncommon entity
Author(s) -
Rajashekara Swamy Meghana,
Pollock Samara,
J. Goldberg Lynne,
Shen Lisa
Publication year - 2021
Publication title -
journal of cutaneous pathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.597
H-Index - 75
eISSN - 1600-0560
pISSN - 0303-6987
DOI - 10.1111/cup.13974
Subject(s) - lymphomatoid papulosis , pathology , medicine , cd30 , lymphoproliferative disorders , cd43 , lymphomatoid granulomatosis , lymphoma , dermatology , cd20
Lymphomatoid papulosis (LyP) type E is a rare variant of the primary cutaneous CD30+ lymphoproliferative disorders, characterized clinically by large necrotic eschar‐like lesions and histopathologically by angiodestructive and angioinvasive infiltrates of CD30+ lymphocytes. As in other forms of lymphomatoid papulosis, type E lesions may undergo spontaneous regression after weeks, with frequent recurrences. We report a 21‐year old male with an angiodestructive infiltrate of CD30+ lymphocytes manifesting as a papular eruption rather than ulceration, and suggest that this clinical phenotype might be related to the presence of CD4+ lymphocytes in the inflammatory cell infiltrate.
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