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Cutaneous intralymphatic anaplastic lymphoma kinase‐negative anaplastic large‐cell lymphoma arising in a patient with multiple rounds of breast implants
Author(s) -
Wang HuanYou,
Thorson John A.,
Hinds Brian R.,
Swalchick William,
Parker Barbara A.,
Chong Alice,
Wallace Anne M.,
Goodman Aaron M.
Publication year - 2021
Publication title -
journal of cutaneous pathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.597
H-Index - 75
eISSN - 1600-0560
pISSN - 0303-6987
DOI - 10.1111/cup.13936
Subject(s) - anaplastic large cell lymphoma , medicine , anaplastic lymphoma kinase , lymphoma , breast implant , dermis , pathology , lymphatic system , differential diagnosis , large cell , breast carcinoma , implant , breast cancer , cancer , surgery , adenocarcinoma , malignant pleural effusion , lung cancer
Primary cutaneous anaplastic large‐cell lymphoma and breast implant‐associated ALCL (BIA‐ALCL) are rare subtypes of anaplastic lymphoma kinase (ALK)‐negative ALCLs originating from skin and breast implants, respectively. Herein, we report a unique case of cutaneous ALK‐negative ALCL occurring in the skin of left medial breast from a patient with multiple rounds of bilateral breast implants and a history of breast carcinoma. The lymphoma cells are entirely confined to the lymphatic channels in the dermis, and the patient has no other areas of skin abnormality, no lymphadenopathy, peri‐implant fluid accumulation, or masses from the bilateral capsules of implants. The differential diagnosis and its relationship with breast implants are further explored.