Premium
Proliferative nodule resembling angiomatoid Spitz tumor with degenerative atypia arising within a giant congenital nevus
Author(s) -
Braunberger Taylor L.,
Adelman Madeline,
Shwayder Tor A.,
Clarke Loren E.,
Friedman Ben J.
Publication year - 2020
Publication title -
journal of cutaneous pathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.597
H-Index - 75
eISSN - 1600-0560
pISSN - 0303-6987
DOI - 10.1111/cup.13840
Subject(s) - spitz nevus , pathology , atypia , congenital melanocytic nevus , nevus , melanoma , nodule (geology) , melanocytic nevus , biology , medicine , cancer research , paleontology
Proliferative nodules arising within congenital melanocytic nevi often present a diagnostic challenge given a close resemblance to melanoma. Several morphologic variants have been characterized. In difficult cases, ancillary molecular tests can be used to better exclude the possibility of malignant degeneration. Herein, we report a case of an unusual proliferative nodule with overlapping features of angiomatoid Spitz tumor and ancient melanocytic nevus, which demonstrated normal findings on both chromosomal microarray and a gene expression profiling assay.