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Subcutaneous desmoplastic small round‐cell tumor: An unusual primary location expanding the differential of superficial round‐cell tumors
Author(s) -
Asadbeigi Sepideh N.,
Zhang Lisheng,
Linos Konstantinos
Publication year - 2020
Publication title -
journal of cutaneous pathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.597
H-Index - 75
eISSN - 1600-0560
pISSN - 0303-6987
DOI - 10.1111/cup.13703
Subject(s) - desmoplastic small round cell tumor , dermatopathology , differential diagnosis , pathology , medicine , immunohistochemistry
Desmoplastic small round‐cell tumor (DSRCT) is a rare, aggressive malignant tumor, which in the great majority of cases arises at abdominal‐pelvic sites. Nevertheless, rare cases of primary extra‐abdominal tumors have been reported. In challenging cases, its molecular hallmark, the EWSR1‐WT1 reciprocal translocation, can be exploited diagnostically by various molecular techniques. Herein, we report an extremely rare case of primary subcutaneous DSRCT in an effort to raise awareness among our dermatopathology colleagues by expanding the differential of superficial round‐cell tumors.