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Verruciform xanthoma accompanying a cystic growth: A case report
Author(s) -
Hara Mariko,
Kato Yoichi,
Kaku Yo,
Tsujioka Kaoru
Publication year - 2020
Publication title -
journal of cutaneous pathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.597
H-Index - 75
eISSN - 1600-0560
pISSN - 0303-6987
DOI - 10.1111/cup.13629
Subject(s) - acanthosis , dermis , pathology , xanthoma , lesion , papillary dermis , reticular dermis , medicine , nodule (geology) , anatomy , epidermis (zoology) , hyperkeratosis , biology , paleontology
Verruciform xanthoma, an uncommon, benign lesion with characteristic histopathological features, usually develops on the oral mucosa or genital area. We present an unusual case of verruciform xanthoma observed on the inguinal skin of a 52‐year‐old healthy man along with an underlying cystic component. The superficial lesion was a pedunculated nodule with a fissured surface and an 18‐mm mound‐like pigmented tumor underneath it. The histopathologically deep lesion was continuously attached to the superficial lesion. It was composed of fistula or sinus‐like spaces and covered with acanthotic epithelium. The epidermis and upper dermis of both lesions showed identical histopathological findings: varying degrees of acanthosis, elongation of rete ridges, eosinophilic parakeratotic layer extending toward the dermis, and densely infiltrating foam cells confined to the papillary layer of the dermis. This finding of a cystic component in the deep dermis expands the histopathologic features of verruciform xanthoma.