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There is fat in this sclerosis: A case report of sclerotic lipoma and review of the literature
Author(s) -
Xiang Yan,
Moshiri Ata S.,
Chan Edward F.,
Dasgupta Trisha S.,
Kozic Heidi,
Elenitsas Rosalie,
Nguyen Cuong V.
Publication year - 2020
Publication title -
journal of cutaneous pathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.597
H-Index - 75
eISSN - 1600-0560
pISSN - 0303-6987
DOI - 10.1111/cup.13593
Subject(s) - lipoma , medicine , pathology , dermatology
Sclerotic lipomas, a lipoma variant, are benign subcutaneous tumors, so‐named because of their resemblance to sclerotic fibromas. Previous literature has suggested that these tumors may show a predilection for middle‐aged adult males. We report an unusual case of a sclerotic lipoma diagnosed on the scalp of a 66‐year‐old female. The patient presented to the outpatient clinic with a 3‐ to 4‐year history of an enlarging and irritated 2.6‐cm nodule on the anterior crown of the scalp, clinically thought to be a pilar cyst. Histopathological examination from the excisional specimen revealed a well‐circumscribed dermal to subcutaneous tumor with ample sclerotic collagen bundles, an increased number of CD34 positive spindled cells, and prominent S‐100 positive mature adipocytes comprising greater than 50% of the tumor. We present this case given its atypical clinical and histopathological presentation, review the literature of sclerotic lipomas, and discuss the differential diagnosis to raise awareness of this rare entity.