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Cutaneous ganglioneuroma: A case report and discussion of the literature
Author(s) -
Segars Kelly A.,
Baltazar David,
Baribault Keith,
Miller Richard A.
Publication year - 2019
Publication title -
journal of cutaneous pathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.597
H-Index - 75
eISSN - 1600-0560
pISSN - 0303-6987
DOI - 10.1111/cup.13419
Subject(s) - ganglioneuroma , ganglion , neural crest , abdomen , abdominal cavity , mediastinum , sympathetic ganglion , pathology , medicine , retroperitoneal space , anatomy , stroma , sympathetic nervous system , nerve sheath , neuroblastoma , immunohistochemistry , biology , radiology , schwannoma , embryo , genetics , microbiology and biotechnology , blood pressure , cell culture
Ganglioneuromas (GNs) are benign tumors composed of ganglion cells in a Schwannian stroma. They are derived from neural crest cells that give rise to the sympathetic nervous system. Hence, GNs can be found anywhere a sympathetic ganglion is present. Most commonly, GNs are found in the posterior mediastinum and abdominal cavity. Within the abdominal cavity, they are most likely to be found in the retroperitoneal space or adrenal glands. Cutaneous involvement is uncommon and rarely reported in literature. We report an interesting case of a cutaneous ganglioneuroma on the abdomen of an 83‐year‐old male.