Premium
Disseminated trichosporonosis with atypical histologic findings in a patient with acute lymphocytic leukemia
Author(s) -
Galligan Eloise R.,
Fix Lindsey,
Husain Sameera,
Zachariah Philip,
Yamashiro Darrell J.,
Lauren Christine T.
Publication year - 2019
Publication title -
journal of cutaneous pathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.597
H-Index - 75
eISSN - 1600-0560
pISSN - 0303-6987
DOI - 10.1111/cup.13397
Subject(s) - grocott's methenamine silver stain , pathology , trichosporon , medicine , staining , periodic acid–schiff stain , biopsy , mycosis , dermatology , chronic lymphocytic leukemia , leukemia , biology , immunology , genetics , yeast
We report a case of disseminated Trichosporon asahii in a patient on systemic antifungal therapy who presented with multiple cutaneous nodules suggestive of fungal infection. Histologic features resembled neutrophilic eccrine hidradenitis but staining with periodic acid‐Schiff and Gomori methenamine silver confirmed the clinical diagnosis. This case highlights the importance of maintaining suspicion for trichosporonosis and contextualizing histologic findings within the underlying clinical picture.