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Erythema elevatum diutinum a rare and poorly understood cutaneous vasculitis: A single institution experience
Author(s) -
Sardiña Luis A.,
Jour George,
Piliang Melissa P.,
Bergfeld Wilma F.
Publication year - 2019
Publication title -
journal of cutaneous pathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.597
H-Index - 75
eISSN - 1600-0560
pISSN - 0303-6987
DOI - 10.1111/cup.13378
Subject(s) - medicine , dermatology , pathology , presentation (obstetrics) , vasculitis , pathological , cutaneous vasculitis , histopathology , dermatopathology , leukocytoclastic vasculitis , scalp , erythema , surgery , disease
Background Erythema elevatum diutinum (EED) is a rare vasculitis with variable clinical presentation which diagnosis can be challenging. Herein we want to describe the clinicopathological spectrum of findings in five cases of EED. Methods We retrospectively analyzed five cases in a single institution collected over a period of 27 years. The clinical history was collected and all the slides were examined to determine the histopathological characteristics of the lesions. Results The mean age of our patients is 56.6 years. Two of five patients were females and with lesions showing predilection for the upper‐extremities. The most common presentation was of an erythematous plaque on the extensor surfaces. Three patients had a history of neoplasm. All cases showed leukocytoclastic damage consistent with EED. Conclusion Our findings suggest that EED shows a heterogeneous clinical and pathological presentation, which can show an overlap with granulomatous dermatoses and mixed connective tissue diseases. Scalp lesions can occur and can mimic granulomatous dermatoses. The finding of EED in benign and malignant solid tumors in three of our patients begs the question whether there is an association between EED and such solid neoplasms.