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Pediatric cutaneous T‐cell post‐transplant lymphoproliferative disorder: Case report and review of the literature
Author(s) -
Rogers Thomas S.,
McGevna Laura,
Cook Deborah L.
Publication year - 2018
Publication title -
journal of cutaneous pathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.597
H-Index - 75
eISSN - 1600-0560
pISSN - 0303-6987
DOI - 10.1111/cup.13331
Subject(s) - lymphoproliferative disorders , medicine , immunosuppression , lymphoma , context (archaeology) , hematopoietic stem cell transplantation , post transplant lymphoproliferative disorder , pathology , transplantation , dermatology , disease , lymphoproliferative disease , immunology , biology , rituximab , paleontology
Post‐transplant lymphoproliferative disease (PTLD) is a rare lymphoid and/or plasmacytic proliferation that occurs in the context of immunosuppression because of solid organ transplantation (SOT) and allogeneic hematopoietic stem cell transplantation (HSCT). PTLD is the most common cancer in children who receive a SOT or HSCT, occurring in up to 13% of these patients. The majority of PTLDs are extracutaneous B‐cell lymphomas, with only 12% to 14%, representing the T‐cell phenotype. PTLDs can involve the skin and behave like an aggressive lymphoma, and are among the most serious and potentially fatal complications of transplantation. Here we present a case report and review of the literature of pediatric cutaneous PTLD.