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Genomic analysis of a case of agminated Spitz nevi and congenital‐pattern nevi arising in extensive nevus spilus
Author(s) -
Porubsky Caitlin,
Teer Jamie K.,
Zhang Yonghong,
Deschaine Maria,
Sondak Ver K.,
Messina Jane L.
Publication year - 2018
Publication title -
journal of cutaneous pathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.597
H-Index - 75
eISSN - 1600-0560
pISSN - 0303-6987
DOI - 10.1111/cup.13082
Subject(s) - spitz nevus , medicine , nevus , dermatology , pathology , melanocytic nevus , melanoma , cancer research
Nevus spilus is a melanocytic neoplasm characterized by a tan macular background punctuated by multiple hyperpigmented macules or papules that represent various types of nevi. These include junctional and compound nevi, Spitz nevi, and rarely blue nevi. We report a unique case of widespread, multiple nevi spili giving rise to agminated Spitz nevi and congenital‐pattern compound nevi. We performed genetic analysis to further characterize the mutational profile of this rare entity.

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