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Benign and malignant hybrid adnexal tumors in a patient with epidermodysplasia verruciformis
Author(s) -
Ho Jonathan D.,
Kam Sarah A.,
AlHaseni Ali,
Markova Alina,
Sahni Debjani,
Lam Christina,
Goldberg Lynne J.,
Bhawan Jag
Publication year - 2017
Publication title -
journal of cutaneous pathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.597
H-Index - 75
eISSN - 1600-0560
pISSN - 0303-6987
DOI - 10.1111/cup.13022
Subject(s) - epidermodysplasia verruciformis , genodermatosis , pityriasis , pathology , medicine , papilloma , dermatology , imiquimod , virus , biology , immunology , biochemistry , gene
Epidermodysplasia verruciformis ( EV ) is a genodermatosis characterized by overgrowth of flat warts, pityriasis versicolor‐like lesions and an increased propensity for developing cutaneous squamous cell carcinomas due to abnormal susceptibility to infection with beta‐human papilloma viruses. Adnexal tumors are not typically associated with EV . Here we report a spectrum of hybrid adnexal tumors with divergent eccrine and folliculosebaceous differentiation, and cytologic features ranging from benign to frankly atypical, in a patient with inherited EV .