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Primary cutaneous CD4 ‐positive small/medium‐sized pleomorphic T‐cell lymphoproliferative disorder: Report of a case and review of the literature
Author(s) -
Keeling Brett H.,
Gavino Alde Carlo P.,
Admirand Joan,
Soldano Anthony C.
Publication year - 2017
Publication title -
journal of cutaneous pathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.597
H-Index - 75
eISSN - 1600-0560
pISSN - 0303-6987
DOI - 10.1111/cup.13011
Subject(s) - medicine , lymphoma , disease , lymphoproliferative disorders , pathology
Primary cutaneous small/medium‐sized T‐cell lymphoma ( PCSM‐TCL ), which was included in the World Health Organization ‐ European Organization for Research and Treatment of Cancer (WHO‐EORTC) classification for cutaneous lymphomas as a provisional entity in 2008, has recently been reclassified as primary cutaneous small/medium‐sized T‐cell lymphoproliferative disorder ( PCSM‐TCLPD ) because of its indolent behavior and uncertain malignant potential. Treatment with local therapies is usually curative, although there have been reports of aggressive, systemic disease. This spectrum of disease behavior evokes the consideration that this entity may actually be multiple diseases with a shared clinicopathologic features rather than a singular disease process with a variety of behaviors. PCSM‐TCLPD retained its designation as a provisional entity under the updated WHO‐EORTC guidelines; however, additional cases of PCSM‐TCLPD are needed to shed more light on this rare disorder.