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Angiotropic syringomatous carcinoma
Author(s) -
Katayama Eri,
Saruta Hiroshi,
Nanri Aya,
Nakama Takekuni,
Ohata Chika
Publication year - 2017
Publication title -
journal of cutaneous pathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.597
H-Index - 75
eISSN - 1600-0560
pISSN - 0303-6987
DOI - 10.1111/cup.12893
Subject(s) - intravasation , dermis , pathology , melanoma , stroma , medicine , carcinoma , anatomy , metastasis , biology , cancer , cancer research , immunohistochemistry
Syringomatous carcinoma ( SC ) is a slow‐growing malignant skin tumor that usually affects the face or scalp. An 83‐year‐old female developed SC on the sole, a rare location. Histopathologically, numerous ducts with few keratinizing cysts were seen in the upper dermis, and cords, strands and nests with sclerotic stroma were seen in the deep dermis and subcutis. In addition to the perineural and intraneural invasion of the tumor, the tumor cells had also invaded the vessel walls. There was no intravasation of tumor cells or interruption of the endothelium. Because melanoma with vascular wall invasion without intravasation of melanoma cells or interruption of the endothelium has been called angiotropic melanoma, we termed the present tumor angiotropic SC . Tumor cells showed wide local invasion.